Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Safety evaluation of <em>FAD2</em> RNAi transgenic <em>Brassica napus</em> L. based on microbial diversity and metabonomic analysis

Mon, 19/12/2022 - 12:00
Front Plant Sci. 2022 Dec 1;13:953476. doi: 10.3389/fpls.2022.953476. eCollection 2022.NO ABSTRACTPMID:36531340 | PMC:PMC9751890 | DOI:10.3389/fpls.2022.953476

Microbiota analysis for risk assessment of xenobiotics: cumulative xenobiotic exposure and impact on human gut microbiota under One Health approach

Mon, 19/12/2022 - 12:00
EFSA J. 2022 Dec 14;20(Suppl 2):e200916. doi: 10.2903/j.efsa.2022.e200916. eCollection 2022 Dec.NO ABSTRACTPMID:36531282 | PMC:PMC9749440 | DOI:10.2903/j.efsa.2022.e200916

Pan-Cancer analysis shows that ACO2 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including hepatocellular carcinoma

Mon, 19/12/2022 - 12:00
Front Oncol. 2022 Nov 30;12:1055376. doi: 10.3389/fonc.2022.1055376. eCollection 2022.NO ABSTRACTPMID:36531056 | PMC:PMC9748622 | DOI:10.3389/fonc.2022.1055376

Glutathione levels are associated with methotrexate resistance in acute lymphoblastic leukemia cell lines

Mon, 19/12/2022 - 12:00
Front Oncol. 2022 Dec 1;12:1032336. doi: 10.3389/fonc.2022.1032336. eCollection 2022.NO ABSTRACTPMID:36531023 | PMC:PMC9751399 | DOI:10.3389/fonc.2022.1032336

A new limit for blood metabolite analysis using <sup>1</sup>H NMR spectroscopy

Mon, 19/12/2022 - 12:00
J Magn Reson Open. 2022 Dec;12-13:100082. doi: 10.1016/j.jmro.2022.100082. Epub 2022 Nov 15.NO ABSTRACTPMID:36530463 | PMC:PMC9757760 | DOI:10.1016/j.jmro.2022.100082

Metabolomic analysis of porcine intestinal epithelial cells during swine acute diarrhea syndrome coronavirus infection

Mon, 19/12/2022 - 12:00
Front Cell Infect Microbiol. 2022 Dec 1;12:1079297. doi: 10.3389/fcimb.2022.1079297. eCollection 2022.NO ABSTRACTPMID:36530441 | PMC:PMC9751206 | DOI:10.3389/fcimb.2022.1079297

Targeting malaria parasites with novel derivatives of azithromycin

Mon, 19/12/2022 - 12:00
Front Cell Infect Microbiol. 2022 Nov 30;12:1063407. doi: 10.3389/fcimb.2022.1063407. eCollection 2022.NO ABSTRACTPMID:36530422 | PMC:PMC9748569 | DOI:10.3389/fcimb.2022.1063407

Identification of nutritional components in unripe and ripe <em>Docynia delavayi (</em>Franch.) Schneid fruit by widely targeted metabolomics

Mon, 19/12/2022 - 12:00
PeerJ. 2022 Dec 12;10:e14441. doi: 10.7717/peerj.14441. eCollection 2022.NO ABSTRACTPMID:36530411 | PMC:PMC9753743 | DOI:10.7717/peerj.14441

Transcriptome and metabolome analyses reveal anthocyanins pathways associated with fruit color changes in plum (<em>Prunus salicina</em> Lindl.)

Mon, 19/12/2022 - 12:00
PeerJ. 2022 Dec 13;10:e14413. doi: 10.7717/peerj.14413. eCollection 2022.NO ABSTRACTPMID:36530399 | PMC:PMC9756864 | DOI:10.7717/peerj.14413

Widely targeted metabolite profiling of mango stem apex during floral induction by compond of mepiquat chloride, prohexadione-calcium and uniconazole

Mon, 19/12/2022 - 12:00
PeerJ. 2022 Dec 12;10:e14458. doi: 10.7717/peerj.14458. eCollection 2022.NO ABSTRACTPMID:36530389 | PMC:PMC9753738 | DOI:10.7717/peerj.14458

Inhomogeneous Phase Significantly Reduces Oral Bioavailability of Felodipine/PVPVA Amorphous Solid Dispersion

Mon, 19/12/2022 - 12:00
Mol Pharm. 2022 Dec 18. doi: 10.1021/acs.molpharmaceut.2c00695. Online ahead of print.NO ABSTRACTPMID:36529939 | DOI:10.1021/acs.molpharmaceut.2c00695

Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000-2018

Sun, 18/12/2022 - 12:00
BMC Med. 2022 Dec 19;20(1):488. doi: 10.1186/s12916-022-02639-z.NO ABSTRACTPMID:36529768 | DOI:10.1186/s12916-022-02639-z

Temperature-dependent metabolite orchestration to acute submaximal exercise indicates cardiorespiratory fitness in humans

Sun, 18/12/2022 - 12:00
Life Sci. 2022 Dec 15:121284. doi: 10.1016/j.lfs.2022.121284. Online ahead of print.NO ABSTRACTPMID:36529280 | DOI:10.1016/j.lfs.2022.121284

Newborn Screening for Cerebrotendinous Xanthomatosis: a retrospective biomarker study using both flow-injection and UPLC-MS/MS analysis in 20.000 newborns

Sun, 18/12/2022 - 12:00
Clin Chim Acta. 2022 Dec 15:S0009-8981(22)01414-0. doi: 10.1016/j.cca.2022.12.011. Online ahead of print.NO ABSTRACTPMID:36529270 | DOI:10.1016/j.cca.2022.12.011

Metabolomics in gestational diabetes mellitus: A review

Sun, 18/12/2022 - 12:00
Clin Chim Acta. 2022 Dec 15:S0009-8981(22)01407-3. doi: 10.1016/j.cca.2022.12.005. Online ahead of print.NO ABSTRACTPMID:36529269 | DOI:10.1016/j.cca.2022.12.005

Metabolomics study of ribavirin in the treatment of orthotopic lung cancer based on UPLC-Q-TOF/MS

Sun, 18/12/2022 - 12:00
Chem Biol Interact. 2022 Dec 15:110305. doi: 10.1016/j.cbi.2022.110305. Online ahead of print.NO ABSTRACTPMID:36529159 | DOI:10.1016/j.cbi.2022.110305

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

Sun, 18/12/2022 - 12:00
EBioMedicine. 2022 Dec 16;87:104408. doi: 10.1016/j.ebiom.2022.104408. Online ahead of print.NO ABSTRACTPMID:36529104 | DOI:10.1016/j.ebiom.2022.104408

A UHPLC-Q-TOF-MS-based serum and urine metabolomics approach reveals the mechanism of Gualou-Xiebai herb pair intervention against atherosclerosis process in ApoE<sup>-/-</sup> mice

Sun, 18/12/2022 - 12:00
J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Dec 13;1215:123567. doi: 10.1016/j.jchromb.2022.123567. Online ahead of print.NO ABSTRACTPMID:36529071 | DOI:10.1016/j.jchromb.2022.123567

Noggin-mediated effects on metabolite profiles of microglia and oligodendrocytes after ischemic insult

Sun, 18/12/2022 - 12:00
J Pharm Biomed Anal. 2022 Dec 5;224:115196. doi: 10.1016/j.jpba.2022.115196. Online ahead of print.NO ABSTRACTPMID:36529041 | DOI:10.1016/j.jpba.2022.115196

A multiomics integrative analysis of color de-synchronization with softening of 'Hass' avocado fruit: A first insight into a complex physiological disorder

Sun, 18/12/2022 - 12:00
Food Chem. 2022 Dec 13;408:135215. doi: 10.1016/j.foodchem.2022.135215. Online ahead of print.NO ABSTRACTPMID:36528992 | DOI:10.1016/j.foodchem.2022.135215

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